p53: The Gene that Cracked the Cancer Code Paperback – May 3, 2016
Author: Sue Armstrong ID: 1472910524
Review
“It’s not the destination that’s important here, but the journey. This is not only a story about the gene on chromosome 17, nor only about the nature of cancer, but also about how science works.” 
“Ms. Armstrong’s book comes alive in the sections where she explores cancer’s human toll . . . She also captures the excitement of researchers as they come upon eureka moments.”
“A brilliant narrative that captures the essence of the scientific challenges faced by researchers in this pursuit and the progress that has been made in our understanding of p53.”
“She covers every aspect of cancer development, giving us a sense of how this evasive illness persists, even in the face of modern medicine . . . It is with hope and hard work that we can look to the future with optimism. ”
About the Author
Sue Armstrong is a science writer and foreign correspondent who has worked for New Scientist and BBC World Service. Since the 1980s, she has undertaken regular assignments for the World Health Organization (WHO) and UNAIDS, writing about health issues. The author of A Matter of Life and Death: Inside the Hidden World of the Pathologist, Armstrong lives in Edinburgh, Scotland.
Paperback: 288 pagesPublisher: Bloomsbury Sigma (May 3, 2016)Language: EnglishISBN-10: 1472910524ISBN-13: 978-1472910523 Product Dimensions: 5 x 1 x 7.8 inches Shipping Weight: 7 ounces (View shipping rates and policies) Best Sellers Rank: #1,572,186 in Books (See Top 100 in Books) #1414 in Books > Medical Books > Medicine > Internal Medicine > Oncology #1869 in Books > Medical Books > Basic Sciences > Genetics #2487 in Books > Health, Fitness & Dieting > Diseases & Physical Ailments > Cancer
If you are fascinated by research–the painstaking and time-consuming studies; the collaboration and the competition among experts searching for breakthroughs; and the surprising role of serendipity–you may find Sue Armstrong’s "p53: The Gene that Cracked the Cancer Code" enlightening and entertaining. This is more than a dry recitation about how brilliant minds all over the world solved a difficult puzzle. It is also a heartbreaking story about unlucky families who have inherited a mutant version of p53 that makes them susceptible to a variety of cancers.
When p53 was identified, no one suspected that it is "a master switch in our cells whose main function is to prevent tumors arising when their DNA is damaged." Since then, p53 has "become the most studied single gene in the history of molecular biology." Scientists in the United States, England, France, Brazil, China, and other countries have devoted a great deal of time, money, and effort to find out where p53 is located, how it works, what happens when it malfunctions, and how it might be used in the battle against cancer.
In spite of Armstrong’s admirable goal to make this work of non-fiction clear to the layperson, many readers will find the material too technical and complex to grasp in its entirety. Still, Armstrong has done her homework, her enthusiasm is infectious, and she effectively elucidates the key points of her thesis. In addition, she introduces us to a variety of researchers, including Bert Vogelstein of Johns Hopkins, who has been involved in the study of p53 for many years, and Arnie Levine of Princeton, one of four individuals who discovered the gene in 1979. Ms.
p53 The Gene that Cracked the Cancer Code Sue P53 THE GENE THAT CRACKED THE CANCER CODE tells the story of the discovery of the gene and of medical 05 03 2016 Paperback Amazon com p53 p53 The Gene that Cracked the Cancer Code Feb 24 2015 4 3 out of 5 stars 16 p53 and Cancer Mar 31 2016 ISSUU Sigma Imprint sample by Bloomsbury Publishing Sigma Imprint sample 80 000 www juleshoward juleshoward P53 The Gene that Cracked the Cancer Code Sue Armstrong All May 2015 HARDBACK
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